Novel alcohol oxidation catalyst

Enables to effectively oxidize sec-alcohol as well as n-alcohol and to oxidized with air

Summary

Alcohol oxidation is one of fundamental reactions in organic chemistry. This reaction is especially useful for synthesizing high-valueadded compounds such as medicine, pesticide, perfume and so on. Although, TEMPO and the related compounds featuring AZADO skeleton (e.g. AZADO, 1-Me-AZADO, and ABNO) are often used as alcohol oxidation catalyst , there are some problems concerning catalytic activity and reaction efficiency.
This invention provides novel alcohol oxidation catalyst “Nor-AZADO” which can effectively oxidize sec-alcohol as well as n-alcohol using air as the terminal oxidant.

Effect & Applications

The advantages of Nor AZADO are as follows.
1. Ultra-high catalytic turnover, enabling efficient oxidation of sec-alcohol
2.Possible to finish the aerobic oxidation in a short reaction time with high catalytic activity

Patent Information

Publication No：WO2012/008228
Inventor ：Prof. IWABUCHI
keyword ： Chemistry