Intestinal bacteria that reduce uremic substances
Intestinal bacteria that reduce p-cresyl sulfate
Overview
Previous studies have shown that several uremic substances, which
cause exacerbation of diabetic nephropathy, are produced by
intestinal bacteria. On the other hand, identification of intestinal
bacterial species involved in the production of uremic substances has
been difficult due to confounding factors such as renal function. The
inventors identified intestinal bacteria involved in the reduction of
uremic substances by analyzing them without confounding factors of
renal function.
The present invention relates to an agent for inhibiting the production
of uremic toxins and a functional food containing these bacteria.
Sesamol has also been proposed as a functional ingredient for
reducing uremic substances by Professor Abe et al., one of the
present inventors.
(Uremic substance reducing agent containing sesame lignan (ttechnoarch.co.jp))
It is expected that the bacteria of the present invention will not be
used as a single agent but will be commercialized aiming at a
synergistic effect by combining with the above functional ingredients.
Results of Oral Administration of Three Bacteria to Renal Failure Mice
Product Application
・Prophylactic or therapeutic agent for chronic kidney disease
・Health food and food for specified health use intended for kidney
care
IP Data
IP No. ： JP2024-055022
Inventor ： ABE Takaaki, TOYOHARA Takafumi, WATANABE Shun, KUJIRAI Ryotau
keyword ： Intestinal bacteria, urinary toxin reduction, kidney care, supplements