Titanium alloy for biomedical application

High antibacterial property, biocompatibility and a low Young's modulus close to the cortical bone

Overview

　A requirement for biocompatible Ti alloy for orthopedic implants is to suppress stress shielding, which occurs because of the large difference between Young’s moduli of the prosthetic stem and the cortical bone (10–30 GPa). Meanwhile, conventional autoclave sterilization before implant exhibits the discoloration and heaviest particulate contamination, and some multiple sterilization regimens for metallic materials may pose serious biological concerns.
　The present invention can provide the necessary functions to a Ti implant material without impairing the low Young's modulus of Ti alloy. It possesses high antibacterial properties with a high antibacterial activity value above 2.0 from the antibacterial test (JIS R 1702) and osseointegration fromhydroxyapatite formation on the surface of Ti alloy in simulated body fluid.

Features・Outstandings

Product Application

・Titanium alloy for biomedical use, especially for artificial prosthetic stem.

Related Works

[1] S. Hanada, N. Masahashi, T.K. Jung, S. Semboshi, Mater. Sci. Eng. A 802 (2021) 140645.
[2] MASAHASHI Naoya, MORI Yu, TANAKA Hidekazu, KOGURE Atsushi, NORO Atsushi, KAMIMURA Masayuki, YAMADA Norikazu, ITOI Eiji, HANADA Shuji, Titanium, 34 (2016) 216－221

IP Data

IP No.　 ： JP2021-074013
Inventor ： MASAHASHI Naoya, HANADA Shuji, MOKUDAI Takayuki, ITOI Eiji, MORI Yu, INOUE Hiroyuki
keyword ： Material, Medical/Welfare device