Urinary toxin reducer with sesamol

Sesamol inhibits enzymes produced by intestinal bacteria

Overview

　Phenyl sulfate(PS) and indoxyl sulfuric(IS) are factor of Diabetic nephropathy(DN). These compounds are produced by the reaction of phenol and indole which are protein metabolites, with tyrosine phenol lyase and tryptophan indole lyase which intestinal bacteria have. Decreasing PS and IS in blood is important for DN treatment.　
　In the present study, certain sesame-derived lignans exhibited TPL and TIL inhibitory activity.

Features・Outstandings

Product Application

・Medicine　　
・Functional food
・Supplement

Related Works

1.Biochemical and Biophysical Research Communications 590 (2022)
158-162. https://doi.org/10.1016/j.bbrc.2021.12.088

IP Data

IP No.　 ： JP2022-135978
Inventor ： Toru Nakayama, Daiki Oikawa, Takaaki Abe　
keyword ： Agriculture, Food item